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Flow Cytometry Testing

1 DNA Ploidy and Cell Cycle Analysis

DNA Ploidy and Cell Cycle Analysis Clinical Significance Nuclear DNA content can be measured and analyzed by flow cytometry to determine the DNA ploidy of the sample. Normal cells have a diploid DNA content while many tumors show cells with an abnormal DNA…

2 Fetal Hemoglobin Detection by Flow Cytometry

Fetal Hemoglobin Detection by Flow Cytometry Clinical Significance: Measurement of fetal cells has traditionally been performed based on the Kleihauer-Betke technique. This is a slide-based microscopic counting method of blood smears, which is laborious and…

3 Hours of Operation

Hours of Operation - Flow Cytometry The flow cytometry lab is operational Monday through Friday 7 am to 5:30 pm Saturday 8:00 am to 4:30 pm Sunday: on call to cover any stat flow cytometry specimen. Please page the on-call pathologist for any flow cytometry…

4 Immunodeficiency Evaluation

Immunodeficiency Evaluation Clinical Significance: Immunodeficiency states can be acquired or congenital. 1. The pathogenesis of acquired immunodeficiency syndrome (AIDS) is largely due to the decrease in number of T-cells that bear the CD4 receptor. Progressive…

5 Leukemia and Lymphoma Evaluations

Leukemia and Lymphoma Evaluation Clinical Significance Leukemia and lymphoma populations display characteristic patterns of antigen expression (CD antigens) on the cell surface or in the cytoplasm. Flow cytometric analysis provides increased sensitivity and…

6 Paroxysmal Nocturnal Hemoglobinuria Analysis

Out of state clients use this requisition when sending PNH testing Paroxysmal Nocturnal Hemoglobinuria (PNH) Requisition for Out of State Clients Paroxysmal Nocturnal Hemoglobinuria (PNH) Clinical Significance: Paroxysmal nocturnal hemoglobinuria (PNH) is…

7 Unacceptable Specimens

Unacceptable Specimens for Flow Cytometry Most specimens for flow cytometric analysis should be analyzed within 24 hours to maintain optimal viability of the cells. This may not always be possible and the ordering labs should contact the flow cytometry lab…